Former Toronto Blue Jays pitcher Brian Wolfe has died at just 45 years old following what his wife described as a “difficult and torturous battle.”

Wolfe’s wife, Rachell, announced the heartbreaking news on Facebook, revealing that the former Major League pitcher died early Tuesday morning.

“I’m sorry to write this but after a really really difficult and torturous battle Brian Wolfe passed away early this morning,” she wrote.

A cause of death has not been publicly disclosed.

The Toronto Blue Jays later confirmed Wolfe’s death and shared a tribute to their former pitcher.

“We are saddened to learn of the passing of former Blue Jay, Brian Wolfe,” the team wrote. “Our thoughts are with his loved ones during this difficult time.”

Wolfe spent three seasons in the major leagues, all with Toronto, after a long journey through the minor leagues.

The Fullerton, California, native was selected by the Minnesota Twins in the sixth round of the 1999 MLB Draft after starring at Servite High School in Anaheim.

He spent several years working his way through Minnesota’s farm system before joining the Milwaukee Brewers organization. Milwaukee later traded him to Toronto in January 2006 in exchange for infielder Corey Koskie.

Wolfe finally reached the majors on May 30, 2007, making his debut against the New York Yankees.

That game immediately put the rookie pitcher at the center of an unusual baseball controversy.

Yankees star Alex Rodriguez was accused of distracting Toronto infielder Howie Clark by shouting while Clark attempted to catch a pop fly. The ball dropped, allowing a run to score — and the run was charged to Wolfe.

Despite the bizarre introduction to the majors, Wolfe quickly became a reliable arm in Toronto’s bullpen.

He made a career-high 38 appearances during his rookie season and posted an impressive 2.98 ERA.

Across three MLB seasons from 2007 through 2009, Wolfe appeared in 72 games, finishing with a 5-5 record and a 3.81 ERA over 82 2/3 innings.

But Wolfe’s baseball career was far from finished when his time in Toronto ended.

He moved to Japan in 2010 and spent another nine seasons pitching in Nippon Professional Baseball for the Hokkaido Nippon-Ham Fighters, Fukuoka SoftBank Hawks and Saitama Seibu Lions.

Wolfe went 56-40 with a 3.43 ERA across 167 appearances in Japan and won back-to-back Japan Series championships with SoftBank in 2014 and 2015.

His time overseas also briefly crossed paths with future MLB superstar Shohei Ohtani.

Wolfe and Ohtani were teammates with the Nippon-Ham Fighters during the 2013 season, Ohtani’s first year playing professionally in Japan. Wolfe later continued his career with SoftBank and Seibu before playing his final professional season in 2018.

Following news of Wolfe’s death, former MLB outfielder Brandon Barnes shared an emotional tribute to the pitcher, describing Wolfe as one of his closest friends and mentors.

Barnes reflected on how suddenly a final conversation with someone can arrive without anyone realizing it at the time.

“Life is too short,” Barnes said in the emotional message, urging people to call the people they love and tell those who changed their lives how much they mean to them.

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